Main mechanism of ALI induced by LPS is that it directly damaged pulmonary alveolar epithelium and vascular endothelium. LPS致ALI的机制主要是直接损伤肺泡上皮和血管内皮细胞。
Objective To investigate the changes of alveolar epithelial permeability and the capacity of alveolar epithelium to remove alveolar fluid in the rat models of acute lung injury induced by oleic acid. 目的观察大鼠油酸型肺损伤时肺泡上皮通透性和肺泡上皮液体清除能力的变化,旨在阐明肺泡上皮屏障功能在渗透性肺水肿发生中的作用。
Histological examination of the PS treated lung showed alveolar expansion and partial release of lamellar bodies from type ⅱ epithelium cells. 光、电镜结果提示PS组肺泡大部分复张,Ⅱ型细胞中板层体颗粒有部分释放。
Extravascular lung water ( EVLW) was measured by gravimetric method. Alveolar epithelium apoptosis was detected by terminal deoxynucleotidyl transferase-mediated dUTP biotin nick end labeling ( TUNEL). 采用末端脱氧核苷酸转移酶介导的dUTP缺口末端标记法(TUNEL)检测肺泡上皮细胞凋亡情况;用重力法测定血管外肺水(EVLW)含量;
Study on the Change of the Expression of Cadherin on Alveolar Epithelium in the Model of Pulmonary Fibrosis 大鼠肺纤维化模型肺泡上皮钙粘素的表达
Alveolar type II cells are the stem cells of alveolar epithelium, they are multifunctional pneumocytes and play a important role in lung fluid transport. 肺泡Ⅱ型细胞是肺泡上皮的干细胞,是一种多功能肺细胞,在肺水转运中起着非常重要的作用。
Conclusions bFGF can promote the repair of trachea mucous membrane and alveolar epithelium of the patients with severe aspiration injury. 结论bFGF能显著促进重度吸入性损伤患者气道粘膜及肺泡的修复。
Type ⅰ cells began to increase in the alveolar epithelium until 32 weeks. 32周时,肺泡的发育逐渐成熟,Ⅰ型肺泡细胞逐渐增多。
Effect of recruitment maneuver on alveolar epithelium barrier in rat with acute lung injury 肺复张手法对急性肺损伤大鼠肺泡上皮细胞屏障功能的影响
Transmission electron microscopic observation of alveolar epithelium and blood-air barrier of human fetus 胎儿肺泡上皮和气血屏障的电镜观察
By the late phase of fetal development or neonatal period, TTF-1 was expressed in only type ⅱ alveolar epithelium cells and their precursor cells, but was absent in ciliated cells and type ⅰ alveolar epithelium cells. 在胎肺发育末期及新生儿肺中,TTF1阳性反应在Ⅱ型肺泡上皮细胞和肺泡前体细胞中稳定表达,纤毛细胞和Ⅰ型肺泡上皮细胞无表达。
In order to investigate the development of the lung, the ultrastructure of alveolar epithelium from 24 human fetuses of 14-40 weeks in gestation age were observed. 为阐明不同胎龄肺泡表面上皮和气血屏障的发育状况,对24例受精龄为14~40周的人胎肺脏,进行透射电镜观察。
Morphological Differences in the Tight Junction of the Freeze-etched Alveolar Epithelium and Capillary Endothelium in Normal Rat with Morphometry 定量观察大鼠肺泡上皮细胞及毛细血管内皮细胞紧密连接冷冻蚀刻的形态学差异
Conclusion Direct injury of SARS-CoV on alveolar epithelium, prominent macrophage infiltration and distinctive fibroblast/ myofibroblast proliferation may play major roles in the pathogenesis of SARS. 结论SARS冠状病毒直接损伤肺泡上皮细胞、巨噬细胞明显浸润和成纤维细胞/肌纤维母细胞显著增生在SARS的致病机制中起重要作用。
Morphology of intercellular junctions of pulmonary capillary endothelium and alveolar epithelium by freeze-fracture technique in oxygen toxic sheep 绵羊氧中毒时肺毛细血管内皮和肺泡上皮细胞连接部的冷冻蚀刻形态变化
Conclusions: Main machanism of ALI induced by LPS directly damaged pulmonary alveolar epithelium and vascular endothelium resulting in pulmonary alveolar capillary barrier dysfunction. This finding led to increase pulmonary vascular permeability and neutrophils infiltration in the pulmonary alveolar cavities. 结论:LPS致ALI的机制主要是直接损伤肺泡上皮和血管内皮细胞致肺泡毛细血管内皮屏障发生障碍,致血管通透性增加和中性粒细胞浸润。
There was no difference in the permeability of alveolar epithelium among ALI, LV and SI groups. 批间C.各组肺泡上皮细胞通透性间比较差异均无显著性。
Objective To observe the repair of trachea mucous membrane and alveolar epithelium in aspiration injury by bronchoalveolar lavage with bFGF. 目的观察使用牛重组碱性成纤维细胞生长因子(bFGF)支气管灌洗治疗吸入性损伤后气管粘膜及肺泡上皮的修复。
PCNA was mainly expressed in alveolar epithelium cells, pulmonary macrophages and inflammatory cells. PCNA蛋白主要在肺泡上皮细胞,支气管上皮细胞,肺泡巨噬细胞和炎症细胞表达。
Effect of Protective Ventilation on the Tight Junction in Alveolar Epithelium of Rats with Acute Lung Injury 保护性通气策略对急性肺损伤大鼠肺泡上皮紧密连接影响的实验研究
OBJECTIVE To investigate the transport profile of recombinant hirudin across xenopus pulmonary membrane and examine the factors influencing the transport, in order to attain primary knowledge on the transport mechanism of hirudin across alveolar epithelium. 目的考察重组水蛭素跨膜转运的基本特点和影响因素,对转运的机制进行初步的探讨,为重组水蛭素肺部给药的体内评价打下理论基础。
Electron microscopic observations of alveoli development and alveolar epithelium differentiation of mouse lung 小鼠肺泡发育与肺泡上皮细胞分化的电镜观察
Electron microscopic study on the alveolar epithelium of the goat fetus 山羊胎儿肺泡上皮的电镜观察
In neonatal lung sections, positive PCNA immunostaining was presented in all air-breathing premature newborn rats within postnatal 14 days, and above 90% PCNA-positive cells were located in airway and alveolar epithelium cells, but they were hardly detected at 21 days; 空气组早产新生大鼠生后14d内肺组织中均有PCNA表达,并且PCNA阳性细胞90%以上定位于气道和肺泡上皮细胞,21d时几乎检测不出其表达;
Immunohistochemistry results showed that PDGF-A was expressed in bronchial epithelium, alveolar epithelium and vascular endothelium of neonatal 1d rat lungs. 免疫组织化学结果:生后1d幼鼠肺组织支气管上皮细胞、肺泡上皮细胞、血管内皮细胞内均可见PDGF-A蛋白表达。
AT ⅱ cells are very important to maintain the normal respiratory function and to restore the integrality of alveolar epithelium. If ATII cells were intensively damaged, lung injury or tissue fibrosis would inevitably occur. ATⅡ细胞对维持正常呼吸功能和肺泡上皮完整有十分重要的作用,如果它过度凋亡,肺损伤和组织纤维化将不可避免。
Components of BALF come from air tube and alveolar epithelium ecderon which can reflect process for affection of lung parenchyma. 支气管肺泡灌洗液(BALF)中的成分来源于气道及肺泡上皮表层,它能反映肺实质的病变过程。